🕹️ Ultra Sensitive Psa Vs Regular Psa

This involved the presence of a PSA greater than 0.2 ng/mL measured 6-13 weeks after RP, followed by a confirmatory test showing a persistent PSA greater than 0.2 ng/mL. 9 Ultra-sensitive PSA assays have recently improved detection levels down to 0.01 ng/mL, and may possibly lead to better treatment outcomes through earlier adoption of
Why then measure lower values? With the ultra sensitive PSA test, normally fluctuations will occur. How will you deal with 0.01 at one test and three months later 0.04? You probably becomes anxious! Unnecessarily. With your pathology - avoid PSA stress and anxiety by continuing with the regular test. PSA at .01 and .02ng are still very low and as noted waiting for another test is the best thing to do, anxiety associated with the waiting and anticipation aside! IMO, Do NOT look for an ultra-sensitive PSA test as it provides no useful diagnostics and only adds to the anxiety when you see that third digit move around.
Prostate specific antigen (psa) is a protein produced only by the prostate gland. The prostate gland is a doughnut-shaped gland located in a man's pelvis in the small space between the base of the penis and the bladder. The prostate makes the fluid that nourishes sperm and carries sperm during ejaculation.
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Ultra-sensitive PSA enables earlier detection of PSA recurrence compared to that with conventional reagents (3-5). However, the effectiveness of additional treatment in regard to PSA recurrence postoperatively in RP cases remains debatable (6,7) and unnecessary treatment should generally be avoided. It is hypothesized that urologists may have
A "normal" PSA level of 4 ng/ml or below doesn't guarantee that you are cancer-free; in about 15% of men with a PSA below 4 ng/ml, a biopsy will reveal prostate cancer. A high PSA level may prompt you to seek treatment, resulting in possible urinary and sexual side effects. Conditions other than cancer—BPH and prostatitis, for example—can
It may take a little longer for the psa to go to undetectable. For 100% success the reading should go to less than .01 after surgery. If the current reading is verified by a second test, sometimes after surgery a little piece of normal prostate tissue is inadvertently left behind, which can cause a residual low psa reading.
PSA has a half-life in the bloodstream of 2 or 3 days. So, if one's PSA level before surgery was 10 ng/mL, as an example, it would take seven half-lives before the PSA fell into the undetectable range (for standard PSA test) of less than 0.1 ng/ml. Example: * start, 10ng/mL. * 1st half-life, down to 5 ng/mL. The PSA levels are different though. Kaiser doesn't do the ultra-sensitive PSA test so I might be closer to detectible PSA (i.e., >.1ng/ml) than I think. I get the sense for other posts that Posted 9/15/2013 1:47 PM (GMT -8) As a relatively recent post prostatectomy patient, I am trying to locate a laboratory in the Midwest or elsewhere that will perform an ultrasensitive PSA analysis that provides readings below 0.015 ng/mL, the threshold now followed by LabCorp. I understand that the Siemens IMMULITE 2000, 2500 and XPi were said The regular PSA is calibrated to be the most accurate at PSA =4.0 and the ultrasensitive is calibrated to be more accurate 0.001 to 4.0 since 0 is impossible. the Standard (Total) PSA, which usually has a reliable sensitivity down to 0.1 ng/ml and the Hyper-sensitive (Total) or Ultra-sensitive (Total) PSA, two terms which are often used Assays that measure PSA to concentrations below 0.1 ng/mL are denoted ultrasensitive PSA (USPSA). The use of USPSA cutpoints below currently recommended PSA thresholds may be helpful in identifying cases of early biochemical recurrence and for selecting patients with adverse clinicopathologic risk factors for secondary therapy.
There are two classes of precision for the so called ultra sensitive test: Reporting to the second vs to the third decimal place. Assessment for the 0.0x class: 0.01 or less -> Excellent prognosis. 0.02 -> Quite common, should be en guard for the future though. 0.03 -> Recurrence probability during the following 2-3 years 50-50%
Mikes21 •. 3 years ago • 29 Replies. Hi All, Five months ago I posted that I went from an ultra sensitive psa of Subscribe To Cancer: Prostate. Several Forum Brothers, here and elsewhere, have reported a Labcorp PSA result of In order to detect ultra-low concentrations of the cancer biomarker PSA, we utilized SiMoA, a recently developed ultra-sensitive ELISA based on single molecule counting technology 9. Introduction Prostate-specific antigen (PSA) is the most widely used tool to detect and monitor prostate cancer (PCa) 1. PSA detection methods with detection levels under 0.1 ng/mL are Ultrasensitive PSA is only useful for PSAs between 0.01-0.10 (thousandths are useless). Shooter1 4 years ago. You are all good. I was 0.12/0.13 area for years but in the last year started to fall. (0.08 to 0.00) Not what I expected to hear but sure feels good to be undetectable for the first time.
c. After the testing is completed, the run number, date of analysis, PSA result, PSA comment, PSA analyst, and the PSA 2.5% repeat results are entered into the result file. d. Data entry is checked for errors. e. After the free PSA testing has also been completed, resulted, and checked, the result file is transmitted electronically to NHANES
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